CFH exerts anti-oxidant effects on retinal pigment epithelial cells independently from protecting against membrane attack complex

Age Related Macular Degeneration (AMD) is the first cause of social blindness in people aged over 65 leading to atrophy of retinal pigment epithelial cells (RPE), photoreceptors and choroids, eventually associated with choroidal neovascularization. Accumulation of undigested cellular debris within R...

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Publicado en:Sci Rep
Main Authors: Borras, Céline, Canonica, Jérémie, Jorieux, Sylvie, Abache, Toufik, El Sanharawi, Mohamed, Klein, Christophe, Delaunay, Kimberley, Jonet, Laurent, Salvodelli, Michèle, Naud, Marie-Christine, Arsenijevic, Yvan, Shalabi, Andrée, Souchaud, Landry, Behar-Cohen, Francine, Dinet, Virginie
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761137/
https://ncbi.nlm.nih.gov/pubmed/31554875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50420-9
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