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Synthesis and Antimicrobial Properties of a Ciprofloxacin and PAMAM-dendrimer Conjugate

Infections caused by bacteria resistant to antibiotics are an increasing problem. Multivalent antibiotics could be a solution. In the present study, a covalent conjugate between Ciprofloxacin and a G0-PAMAM dendrimer has been synthesized and tested against clinically relevant Gram-positive and Gram-...

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Bibliographic Details
Published in:Molecules
Main Authors: Svenningsen, Søren Wedel, Frederiksen, Rikki Franklin, Counil, Claire, Ficker, Mario, Leisner, Jørgen J., Christensen, Jørn Bolstad
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146445/
https://ncbi.nlm.nih.gov/pubmed/32197523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25061389
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