Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori

Taking palmatine (PMT) as the lead, 20 new PMT derivatives were synthesized and examined for their antibacterial activities against six tested metronidazole (MTZ)-resistant Helicobacter pylori (H. pylori) strains. The structure–activity relationship (SAR) indicated that the introduction of a suitabl...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Fan, Tianyun, Guo, Xixi, Zeng, Qingxuan, Wei, Wei, You, Xuefu, Pang, Jing, Wang, Yanxiang, Song, Danqing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146163/
https://ncbi.nlm.nih.gov/pubmed/32188132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25061352
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