Multiple BCL2 mutations cooccurring with Gly101Val emerge in chronic lymphocytic leukemia progression on venetoclax

Antzeko izenburuak

• Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations
  nork: Birkinshaw, Richard W., et al.
  Argitaratua: (2019)
• ASXL1 c.1934dup;p.Gly646Trpfs*12—a true somatic alteration requiring a new approach
  nork: Yannakou, Costas K., et al.
  Argitaratua: (2017)
• Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia (Comment to Tausch et al.)
  nork: Weiss, Jonathan, et al.
  Argitaratua: (2019)
• BTK inhibitor therapy is effective in patients with CLL resistant to venetoclax
  nork: Lin, Victor S., et al.
  Argitaratua: (2020)
• Clonal independence of JAK2 and CALR or MPL mutations in comutated myeloproliferative neoplasms demonstrated by single cell DNA sequencing
  nork: Thompson, Ella R., et al.
  Argitaratua: (2020)