CDKN2A homozygous deletion is a strong adverse prognosis factor in diffuse malignant IDH-mutant gliomas

BACKGROUND: The 2016 World Health Organization (WHO) classification of central nervous system tumors stratifies isocitrate dehydrogenase (IDH)–mutant gliomas into 2 major groups depending on the presence or absence of 1p/19q codeletion. However, the grading system remains unchanged and it is now con...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Appay, Romain, Dehais, Caroline, Maurage, Claude-Alain, Alentorn, Agusti, Carpentier, Catherine, Colin, Carole, Ducray, François, Escande, Fabienne, Idbaih, Ahmed, Kamoun, Aurélie, Marie, Yannick, Mokhtari, Karima, Tabouret, Emeline, Trabelsi, Nesrine, Uro-Coste, Emmanuelle, Delattre, Jean-Yves, Figarella-Branger, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145561/
https://ncbi.nlm.nih.gov/pubmed/31832685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz124
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