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PL1.1 CDKN2A homozygous deletion is a strong adverse prognosis factor in diffuse malignant IDHmutant gliomas

The 2016 WHO classification of the central nervous system tumors stratifies diffuse adult gliomas into three major groups depending on the presence or absence of two main genetic alterations: IDH mutation and 1p/19q-codeletion. However, the grading system initially based on histological criteria rem...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Appay, R, Dehais, C, Colin, C, Alentorn, A, Carpentier, C, Ducray, F, Ibdaih, A, Kamoun, A, Mokhtari, K, Tabouret, E, Uro-Coste, E, Delattre, J, Figarella-Branger, D
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787066/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.000
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