Immunodomination of Serotype-Specific CD4+ T-Cell Epitopes Contributed to the Biased Immune Responses Induced by a Tetravalent Measles-Vectored Dengue Vaccine

Dengue is an emerging mosquito-borne disease, and the use of prophylactic vaccines is still limited. We previously developed a tetravalent dengue vaccine (rMV-TDV) by a recombinant measles virus (MV) vector expressing envelope protein domain III (ED3). In this study, we used dengue-susceptible AG129...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lin, Tsung-Han, Chen, Hsin-Wei, Hsiao, Yu-Ju, Yan, Jia-Ying, Chiang, Chen-Yi, Chen, Mei-Yu, Hu, Hui-Mei, Wu, Szu-Hsien, Pan, Chien-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145397/
https://ncbi.nlm.nih.gov/pubmed/32300346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00546
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