The Immunodominance Change and Protection of CD4(+) T-Cell Responses Elicited by an Envelope Protein Domain III-Based Tetravalent Dengue Vaccine in Mice

Dengue is the leading cause of mosquito-borne viral infections and no vaccine is available now. Envelope protein domain III (ED3) is the major target for the binding of dengue virus neutralizing antibodies; however, the ED3-specifc T-cell response is less well understood. To investigate the T-cell r...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Hsin-Wei, Hu, Hui-Mei, Wu, Szu-Hsien, Chiang, Chen-Yi, Hsiao, Yu-Ju, Wu, Chia-Kai, Hsieh, Chun-Hsiang, Chung, Han-Hsuan, Chong, Pele, Leng, Chih-Hsiang, Pan, Chien-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695087/
https://ncbi.nlm.nih.gov/pubmed/26714037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145717
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