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Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody
OBJECTIVE: Monoclonal antibody derivatives are promising drugs for the treatment of various diseases due to their high matrix metalloproteinases (MMP) active site specificity. We studied the effects of a novel antibody, SDS3, which specifically recognizes the mature active site of MMP9/2 during vent...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7145114/ https://ncbi.nlm.nih.gov/pubmed/32271823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231202 |
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