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Tumor-derived soluble CD155 inhibits DNAM-1–mediated antitumor activity of natural killer cells
CD155 is a ligand for DNAM-1, TIGIT, and CD96 and is involved in tumor immune responses. Unlike mouse cells, human cells express both membranous CD155 and soluble CD155 (sCD155) encoded by splicing isoforms of CD155. However, the role of sCD155 in tumor immunity remains unclear. Here, we show that,...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144518/ https://ncbi.nlm.nih.gov/pubmed/32040157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191290 |
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