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Virtual screening for potential inhibitors of β(1,3)-D-glucan synthase as drug candidates against fungal cell wall
BACKGROUND: To enhance the outcome in patients with invasive candidiasis, initiation of an efficient antifungal treatment in a suitable dosage is necessary. Echinocandins (e.g. caspofungin) inhibit the enzyme β(1,3)-D-glucan synthase of the fungal cell wall. Compared to azoles and other antifungal a...
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| Publicado no: | J Drug Assess |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144292/ https://ncbi.nlm.nih.gov/pubmed/32284908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21556660.2020.1734010 |
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