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Length specificity and polymerization mechanism of (1,3)-β-D-glucan synthase in fungal cell wall biosynthesis

(1,3)-β-D-Glucan synthase (GS) catalyzes formation of the linear (1,3)-β-D-glucan in the fungal cell wall, and is a target of clinically approved antifungal antibiotics. The catalytic subunit of GS, FKS protein, does not exhibit significant sequence homologies to other glycosyltransferases, and thus...

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Bibliografiset tiedot
Julkaisussa:Biochemistry
Päätekijät: Chhetri, Abhishek, Loksztejn, Anna, Nguyen, Hai, Pianalto, Kaila M., Kim, Mi Jung, Hong, Jiyong, Alspaugh, J. Andrew, Yokoyama, Kenichi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015794/
https://ncbi.nlm.nih.gov/pubmed/31899625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00896
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