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Design, synthesis and anticancer activity of naphthoquinone derivatives

Basis on molecular docking and pharmacophore analysis of naphthoquinone moiety, a total of 23 compounds were designed and synthesised. With the help of reverse targets searching, anti-cancer activity was preliminarily evaluated, most of them are effective against some tumour cells, especially compou...

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Bibliografiska uppgifter
I publikationen:J Enzyme Inhib Med Chem
Huvudupphovsmän: Shen, Xiao-bao, Wang, Yang, Han, Xuan-zhen, Sheng, Liang-quan, Wu, Fu-fang, Liu, Xinhua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2020
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144209/
https://ncbi.nlm.nih.gov/pubmed/32200656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1740693
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