Φορτώνει......
RhoBTB Proteins Regulate the Hippo Pathway by Antagonizing Ubiquitination of LKB1
The Hippo pathway regulates growth and apoptosis. We identify RhoBTB proteins as novel regulators of Hippo signaling. RhoBTB depletion in the Drosophila wing disc epithelium cooperated with Yki to drive hyperplasia into neoplasia. Depletion of RhoBTB2 caused elevated YAP activity in human cells. Rho...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | G3 (Bethesda) |
|---|---|
| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Genetics Society of America
2020
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144079/ https://ncbi.nlm.nih.gov/pubmed/32111652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.120.401038 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|