Synthesis, Pharmacological and Structural Characterization of Novel Conopressins from Conus miliaris

Cone snails produce a fast-acting and often paralyzing venom, largely dominated by disulfide-rich conotoxins targeting ion channels. Although disulfide-poor conopeptides are usually minor components of cone snail venoms, their ability to target key membrane receptors such as GPCRs make them highly v...

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Udgivet i:Mar Drugs
Main Authors: Giribaldi, Julien, Ragnarsson, Lotten, Pujante, Tom, Enjalbal, Christine, Wilson, David, Daly, Norelle L., Lewis, Richard J., Dutertre, Sebastien
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7143535/
https://ncbi.nlm.nih.gov/pubmed/32155768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18030150
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