Astrocytes Are Required for Oligodendrocyte Survival and Maintenance of Myelin Compaction and Integrity

Astrocytes have been implicated in regulating oligodendrocyte development and myelination in vitro, although their functions in vivo remain less well defined. Using a novel approach to locally ablate GFAP+ astrocytes, we demonstrate that astrocytes are required for normal CNS myelin compaction durin...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Tognatta, Reshmi, Karl, Molly T., Fyffe-Maricich, Sharyl L., Popratiloff, Anastas, Garrison, Eric D., Schenck, Jessica K., Abu-Rub, Mohammad, Miller, Robert H.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142332/
https://ncbi.nlm.nih.gov/pubmed/32300294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00074
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