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Astrocytes Are Required for Oligodendrocyte Survival and Maintenance of Myelin Compaction and Integrity

Astrocytes have been implicated in regulating oligodendrocyte development and myelination in vitro, although their functions in vivo remain less well defined. Using a novel approach to locally ablate GFAP+ astrocytes, we demonstrate that astrocytes are required for normal CNS myelin compaction durin...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Tognatta, Reshmi, Karl, Molly T., Fyffe-Maricich, Sharyl L., Popratiloff, Anastas, Garrison, Eric D., Schenck, Jessica K., Abu-Rub, Mohammad, Miller, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142332/
https://ncbi.nlm.nih.gov/pubmed/32300294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00074
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