Lack of Conventional Acinar Cells in Parotid Salivary Gland of Patient Taking an Anti-PD-L1 Immune Checkpoint Inhibitor

Background: Salivary glands (SGs) can be damaged by immune checkpoint inhibitor (ICI) therapy. In patients with ICI-induced SG dysfunction, 60% progress to fulfill classification criteria for primary Sjögren's syndrome (pSS), owing to immune foci in SGs and/or anti-SSA autoantibody positivity....

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Pringle, Sarah, van der Vegt, Bert, Wang, Xiaoyan, van Bakelen, Nico, Hiltermann, T. Jeroen N., Spijkervet, Fred K. L., Vissink, Arjan, Kroese, Frans G. M., Bootsma, Hendrika
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142242/
https://ncbi.nlm.nih.gov/pubmed/32300556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00420
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