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PAM3 protects against DSS-induced colitis by altering the M2:M1 ratio

Inflammation of the gastrointestinal tract contributes to the development of inflammatory bowel disease (IBD). Human IBD is modeled by administering dextran sulfate sodium (DSS) to mice. In humans and mice, inflammatory M1 macrophages contribute to the progression of IBD whereas immunosuppressive M2...

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發表在:Sci Rep
Main Authors: Horuluoglu, Begum H., Kayraklioglu, Neslihan, Tross, Debra, Klinman, Dennis
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142137/
https://ncbi.nlm.nih.gov/pubmed/32269253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63143-z
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