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PAM3 supports the generation of M2-like macrophages from lupus patient monocytes and improves disease outcome in murine lupus
Systematic Lupus Erythematosus (SLE) is an autoimmune syndrome of unclear etiology. While T and B cell abnormalities contribute to disease pathogenesis, recent work suggests that inflammatory M1-like macrophages also play a role. Previous work showed that the TLR2/1 agonist PAM3CSK4 (PAM3) could sti...
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| Publicado no: | J Autoimmun |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462249/ https://ncbi.nlm.nih.gov/pubmed/30679006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2019.01.004 |
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