Defining genetic risk factors for scleroderma-associated interstitial lung disease: IRF5 and STAT4 gene variants are associated with scleroderma while STAT4 is protective against scleroderma-associated interstitial lung disease

Although several genetic associations with scleroderma (SSc) are defined, very little is known on genetic susceptibility to SSc-associated interstitial lung disease (SSc-ILD). A number of common polymorphisms have been associated with SSc-ILD, but most have not been replicated in separate population...

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Detalhes bibliográficos
Publicado no:Clin Rheumatol
Main Authors: Stock, Carmel J. W., De Lauretis, Angelo, Visca, Dina, Daccord, Cecile, Kokosi, Maria, Kouranos, Vasilis, Margaritopoulos, George, George, Peter M., Molyneaux, Philip L., Nihtyanova, Svetlana, Chua, Felix, Maher, Toby M., Ong, Voon, Abraham, David J., Denton, Christopher P., Wells, Athol U., Wain, Louise V., Renzoni, Elisabetta A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer London 2020
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142048/
https://ncbi.nlm.nih.gov/pubmed/31916109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10067-019-04922-6
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