Age-Dependent Effects of Type I and Type III IFNs in the Pathogenesis of Bordetella pertussis Infection and Disease

Type I and III IFNs play diverse roles in bacterial infections, being protective for some but deleterious for others. Using RNA-sequencing transcriptomics we investigated lung gene expression responses to Bordetella pertussis infection in adult mice, revealing that type I and III IFN pathways may pl...

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Bibliographic Details
Published in:J Immunol
Main Authors: Ardanuy, Jeremy, Scanlon, Karen, Skerry, Ciaran, Fuchs, Serge Y., Carbonetti, Nicholas H.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141952/
https://ncbi.nlm.nih.gov/pubmed/32152071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900912
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