Llwytho...

Evolution-driven attenuation of alphaviruses highlights key glycoprotein determinants regulating viral infectivity and dissemination

Understanding the fundamental mechanisms of arbovirus transmission and pathogenesis is essential to develop strategies for treatment and prevention. We previously took an in vivo evolution-based approach and identified the chikungunya virus E1 glycoprotein residue 80 to play a critical role in viral...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Noval, Maria G., Rodriguez-Rodriguez, Bruno A., Rangel, Margarita V., Stapleford, Kenneth A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141928/
https://ncbi.nlm.nih.gov/pubmed/31291581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.022
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