Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39

Hepatocyte growth factor (HGF) is a multifunctional protein that signals through the MET receptor. HGF stimulates cell proliferation, cell dispersion, neuronal survival, and wound healing. In the inner ear, levels of HGF must be fine-tuned for normal hearing. In mice, a deficiency of HGF expression...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Morell, Robert J., Olszewski, Rafal, Tona, Risa, Leitess, Samuel, Wafa, Talah T., Taukulis, Ian, Schultz, Julie M., Thomason, Elizabeth J., Richards, Keri, Whitley, Brittany N., Hill, Connor, Saunders, Thomas, Starost, Matthew F., Fitzgerald, Tracy, Wilson, Elizabeth, Ohyama, Takahiro, Friedman, Thomas B., Hoa, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2020
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141880/
https://ncbi.nlm.nih.gov/pubmed/32152201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2278-19.2020
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