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Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39

Hepatocyte growth factor (HGF) is a multifunctional protein that signals through the MET receptor. HGF stimulates cell proliferation, cell dispersion, neuronal survival, and wound healing. In the inner ear, levels of HGF must be fine-tuned for normal hearing. In mice, a deficiency of HGF expression...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Morell, Robert J., Olszewski, Rafal, Tona, Risa, Leitess, Samuel, Wafa, Talah T., Taukulis, Ian, Schultz, Julie M., Thomason, Elizabeth J., Richards, Keri, Whitley, Brittany N., Hill, Connor, Saunders, Thomas, Starost, Matthew F., Fitzgerald, Tracy, Wilson, Elizabeth, Ohyama, Takahiro, Friedman, Thomas B., Hoa, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141880/
https://ncbi.nlm.nih.gov/pubmed/32152201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2278-19.2020
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