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DeepMSA: constructing deep multiple sequence alignment to improve contact prediction and fold-recognition for distant-homology proteins

MOTIVATION: The success of genome sequencing techniques has resulted in rapid explosion of protein sequences. Collections of multiple homologous sequences can provide critical information to the modeling of structure and function of unknown proteins. There are however no standard and efficient pipel...

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Zhang, Chengxin, Zheng, Wei, Mortuza, S M, Li, Yang, Zhang, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141871/
https://ncbi.nlm.nih.gov/pubmed/31738385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz863
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