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All-FIT: allele-frequency-based imputation of tumor purity from high-depth sequencing data
SUMMARY: Clinical sequencing aims to identify somatic mutations in cancer cells for accurate diagnosis and treatment. However, most widely used clinical assays lack patient-matched control DNA and additional analysis is needed to distinguish somatic and unfiltered germline variants. Such computation...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7141867/ https://ncbi.nlm.nih.gov/pubmed/31750888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz865 |
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