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Accurate detection of short and long active ORFs using Ribo-seq data

MOTIVATION: Ribo-seq, a technique for deep-sequencing ribosome-protected mRNA fragments, has enabled transcriptome-wide monitoring of translation in vivo. It has opened avenues for re-evaluating the coding potential of open reading frames (ORFs), including many short ORFs that were previously presum...

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Pubblicato in:Bioinformatics
Autori principali: Choudhary, Saket, Li, Wenzheng, D. Smith, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141849/
https://ncbi.nlm.nih.gov/pubmed/31750902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz878
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