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Orthotopic implantation achieves better engraftment and faster growth than subcutaneous implantation in breast cancer patient-derived xenografts

BACKGROUND: Patient-Derived Xenograft (PDX) is now accepted as a murine model that better mimics human cancer when compared to a conventional cancer cell-line inoculation model. Some claim the advantage of orthotopic site implantation of patient tumor (OS) over ectopic implantation into the subcutan...

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Dades bibliogràfiques
Publicat a:J Mammary Gland Biol Neoplasia
Autors principals: Okano, Maiko, Oshi, Masanori, Butash, Ali, Okano, Ichiro, Saito, Katsuharu, Kawaguchi, Tsutomu, Nagahashi, Masayuki, Kono, Koji, Ohtake, Toru, Takabe, Kazuaki
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141774/
https://ncbi.nlm.nih.gov/pubmed/32109311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-020-09442-7
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