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Endogenous Apelin Is Protective Against Age-Associated Loss of Retinal Ganglion Cells in Mice
Age-associated loss of retinal ganglion cells (RGCs) causes visual deficits, but there is not yet any therapeutic agent to prevent the loss of these cells. Herein, we report that apelin, an endogenous peptide ligand of APJ receptor, is protective against the age-related loss of RGCs in mice. The mRN...
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| izdano v: | Front Aging Neurosci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7141441/ https://ncbi.nlm.nih.gov/pubmed/32296325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00058 |
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