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Does DNA Methylation Matter in FSHD?

Facioscapulohumeral muscular dystrophy (FSHD) has been associated with the genetic and epigenetic molecular features of the CpG-rich D4Z4 repeat tandem array at 4q35. Reduced DNA methylation of D4Z4 repeats is considered part of the FSHD mechanism and has been proposed as a reliable marker in the FS...

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Détails bibliographiques
Publié dans:Genes (Basel)
Auteurs principaux: Salsi, Valentina, Magdinier, Frédérique, Tupler, Rossella
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140823/
https://ncbi.nlm.nih.gov/pubmed/32121044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11030258
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