Oral Administration of Alpha Linoleic Acid Rescues Aβ-Induced Glia-Mediated Neuroinflammation and Cognitive Dysfunction in C57BL/6N Mice

In this work, we evaluated the effects of alpha linoleic acid (ALA), an omega-3 polyunsaturated fatty acid, on amyloid-beta-induced glial-cell-mediated neuroinflammation, amyloidogenesis, and cognitive dysfunction in mice. After an infusion of Aβ(1–42) (Aβ(1–42), 5 μL/5 min/mouse, intracerebroventri...

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Pubblicato in:Cells
Autori principali: Ali, Waqar, Ikram, Muhammad, Park, Hyun Young, Jo, Min Gi, Ullah, Rahat, Ahmad, Sareer, Abid, Noman Bin, Kim, Myeong Ok
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140708/
https://ncbi.nlm.nih.gov/pubmed/32182943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030667
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