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Glucose Metabolic Reprogramming of ER(+) Breast Cancer in Acquired Resistance to the CDK4/6 Inhibitor Palbociclib

The majority of breast cancers express the estrogen receptor (ER) and are dependent on estrogen for their growth and survival. Endocrine therapy (ET) is the standard of care for these tumors. However, a superior outcome is achieved in a subset of ER positive (ER(+))/human epidermal growth factor rec...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Lorito, Nicla, Bacci, Marina, Smiriglia, Alfredo, Mannelli, Michele, Parri, Matteo, Comito, Giuseppina, Ippolito, Luigi, Giannoni, Elisa, Bonechi, Martina, Benelli, Matteo, Migliaccio, Ilenia, Malorni, Luca, Chiarugi, Paola, Morandi, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140692/
https://ncbi.nlm.nih.gov/pubmed/32164162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030668
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