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Is T Cell Negative Selection a Learning Algorithm?

Our immune system can destroy most cells in our body, an ability that needs to be tightly controlled. To prevent autoimmunity, the thymic medulla exposes developing T cells to normal “self” peptides and prevents any responders from entering the bloodstream. However, a substantial number of self-reac...

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Bibliographic Details
Published in:Cells
Main Authors: Wortel, Inge M. N., Keşmir, Can, de Boer, Rob J., Mandl, Judith N., Textor, Johannes
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140671/
https://ncbi.nlm.nih.gov/pubmed/32168897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030690
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