Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP

Arginine-vasopressin (AVP) facilitates water reabsorption in renal collecting duct principal cells through regulation of the water channel aquaporin-2 (AQP2). The hormone binds to vasopressin V2 receptors (V2R) on the surface of the cells and stimulates cAMP synthesis. The cAMP activates protein kin...

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Publicat a:Cells
Autors principals: Dema, Alessandro, Faust, Dörte, Lazarow, Katina, Wippich, Marc, Neuenschwander, Martin, Zühlke, Kerstin, Geelhaar, Andrea, Pallien, Tamara, Hallscheidt, Eileen, Eichhorst, Jenny, Wiesner, Burkhard, Černecká, Hana, Popp, Oliver, Mertins, Philipp, Dittmar, Gunnar, von Kries, Jens Peter, Klussmann, Enno
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140648/
https://ncbi.nlm.nih.gov/pubmed/32164329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030673
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