Small-Molecule Screening Identifies Modulators of Aquaporin-2 Trafficking

In the principal cells of the renal collecting duct, arginine vasopressin (AVP) stimulates the synthesis of cAMP, leading to signaling events that culminate in the phosphorylation of aquaporin-2 water channels and their redistribution from intracellular domains to the plasma membrane via vesicular t...

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Main Authors: Bogum, Jana, Faust, Dörte, Zühlke, Kerstin, Eichhorst, Jenny, Moutty, Marie C., Furkert, Jens, Eldahshan, Adeeb, Neuenschwander, Martin, von Kries, Jens Peter, Wiesner, Burkhard, Trimpert, Christiane, Deen, Peter M.T., Valenti, Giovanna, Rosenthal, Walter, Klussmann, Enno
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2013
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636789/
https://ncbi.nlm.nih.gov/pubmed/23559583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012030295
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