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Restoring Apoptosis with BH3 Mimetics in Mature B-Cell Malignancies
Apoptosis is a highly conserved mechanism enabling the removal of unwanted cells. Mitochondrial apoptosis is governed by the B-cell lymphoma (BCL-2) family, including anti-apoptotic and pro-apoptotic proteins. Apoptosis evasion by dysregulation of anti-apoptotic BCL-2 members (BCL-2, MCL-1, BCL-X(L)...
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| Udgivet i: | Cells |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7140641/ https://ncbi.nlm.nih.gov/pubmed/32183335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030717 |
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