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Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy

Receptor tyrosine kinases (RTKs) are key regulatory signaling proteins governing cancer cell growth and metastasis. During the last two decades, several molecules targeting RTKs were used in oncology as a first or second line therapy in different types of cancer. However, their effectiveness is limi...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pottier, Charles, Fresnais, Margaux, Gilon, Marie, Jérusalem, Guy, Longuespée, Rémi, Sounni, Nor Eddine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140093/
https://ncbi.nlm.nih.gov/pubmed/32244867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030731
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