A Disintegrin and Metalloproteinase 9 (ADAM9) in Advanced Hepatocellular Carcinoma and Their Role as a Biomarker During Hepatocellular Carcinoma Immunotherapy

The chemotherapeutics sorafenib and regorafenib inhibit shedding of MHC class I-related chain A (MICA) from hepatocellular carcinoma (HCC) cells by suppressing a disintegrin and metalloprotease 9 (ADAM9). MICA is a ligand for natural killer (NK) group 2 member D (NKG2D) and is expressed on tumor cel...

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Publicado en:Cancers (Basel)
Main Authors: Oh, Sooyeon, Park, YoungJoon, Lee, Hyun-Jung, Lee, Jooho, Lee, Soo-Hyeon, Baek, Young-Seok, Chun, Su-Kyung, Lee, Seung-Min, Kim, Mina, Chon, Young-Eun, Ha, Yeonjung, Cho, Yuri, Kim, Gi Jin, Hwang, Seong-Gyu, Kwack, KyuBum
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140088/
https://ncbi.nlm.nih.gov/pubmed/32245188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030745
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