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Prevention of Doxorubicin-Induced Autophagy Attenuates Oxidative Stress and Skeletal Muscle Dysfunction

Clinical use of the chemotherapeutic doxorubicin (DOX) promotes skeletal muscle atrophy and weakness, adversely affecting patient mobility and strength. Although the mechanisms responsible for DOX-induced skeletal muscle dysfunction remain unclear, studies implicate the significant production of rea...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Doerr, Vivian, Montalvo, Ryan N., Kwon, Oh Sung, Talbert, Erin E., Hain, Brian A., Houston, Fraser E., Smuder, Ashley J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139604/
https://ncbi.nlm.nih.gov/pubmed/32210013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9030263
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