New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells

In this paper, a novel series of imidazole-based heme oxygenase-1 (HO-1) inhibitors is reported. These compounds were obtained by modifications of previously described high potent and selective arylethanolimidazoles. In particular, simplification of the central linker and repositioning of the hydrop...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Ciaffaglione, Valeria, Intagliata, Sebastiano, Pittalà, Valeria, Marrazzo, Agostino, Sorrenti, Valeria, Vanella, Luca, Rescifina, Antonio, Floresta, Giuseppe, Sultan, Ameera, Greish, Khaled, Salerno, Loredana
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139504/
https://ncbi.nlm.nih.gov/pubmed/32168943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21061923
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