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Superoxide increases surface NKCC2 in the rat thick ascending limbs via PKC
The apical Na(+)-K(+)-2Cl(−) cotransporter (NKCC2) mediates NaCl reabsorption by the thick ascending limb (TAL). The free radical superoxide ([Formula: see text]) stimulates TAL NaCl absorption by enhancing NKCC2 activity. In contrast, nitric oxide (NO) scavenges [Formula: see text] and inhibits NKC...
Sparad:
| I publikationen: | Am J Physiol Renal Physiol |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Physiological Society
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7139495/ https://ncbi.nlm.nih.gov/pubmed/31091128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00232.2018 |
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