MDM2, MDM4 and EGFR Amplifications and Hyperprogression in Metastatic Acral and Mucosal Melanoma

Background: Mucosal and acral melanoma respond worse to immune checkpoint inhibitors (ICI) than cutaneous melanoma. MDM2/4 as well as EGFR amplifications are supposed to be associated with hyperprogression on ICI in diverse cancers. We therefore investigated the response of metastatic acral and muco...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Forschner, Andrea, Hilke, Franz-Joachim, Bonzheim, Irina, Gschwind, Axel, Demidov, German, Amaral, Teresa, Ossowski, Stephan, Riess, Olaf, Schroeder, Christopher, Martus, Peter, Klumpp, Bernhard, Gonzalez-Menendez, Irene, Garbe, Claus, Niessner, Heike, Sinnberg, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139387/
https://ncbi.nlm.nih.gov/pubmed/32110946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030540
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