Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium

UDP-glucose (UDP-Glc) is synthesized by UGP2-encoded UDP-Glc pyrophosphorylase (UGP) and is required for glycoconjugate biosynthesis and galactose metabolism because it is a uridyl donor for galactose-1-P (Gal1P) uridyltransferase. Chinese hamster lung fibroblasts harboring a hypomrphic UGP(G116D) v...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Durrant, Christelle, Fuehring, Jana I., Willemetz, Alexandra, Chrétien, Dominique, Sala, Giusy, Ghidoni, Riccardo, Katz, Abram, Rötig, Agnès, Thelestam, Monica, Ermonval, Myriam, Moore, Stuart E. H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139386/
https://ncbi.nlm.nih.gov/pubmed/32188137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21062028
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados