β(3)-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes

Cardiomyocyte β(3)-adrenoceptors (β(3)-ARs) coupled to soluble guanylyl cyclase (sGC)-dependent production of the second messenger 3’,5’-cyclic guanosine monophosphate (cGMP) have been shown to protect from heart failure. However, the exact localization of these receptors to fine membrane structures...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Schobesberger, Sophie, Wright, Peter T, Poulet, Claire, Sanchez Alonso Mardones, Jose L, Mansfield, Catherine, Friebe, Andreas, Harding, Sian E, Balligand, Jean-Luc, Nikolaev, Viacheslav O, Gorelik, Julia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2020
Aiheet:
Cell Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138611/
https://ncbi.nlm.nih.gov/pubmed/32228862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52221
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