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A 6-nm ultra-photostable DNA FluoroCube for fluorescence imaging

Photobleaching limits extended imaging of fluorescent biological samples. Here, we developed DNA based “FluoroCubes” that are similar in size to the green fluorescent protein (GFP), have single-point attachment to proteins, have a ~54-fold higher photobleaching lifetime and emit ~43-fold more photon...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Niekamp, Stefan, Stuurman, Nico, Vale, Ronald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138518/
https://ncbi.nlm.nih.gov/pubmed/32203385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-0782-3
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