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A 6-nm ultra-photostable DNA FluoroCube for fluorescence imaging

Photobleaching limits extended imaging of fluorescent biological samples. Here, we developed DNA based “FluoroCubes” that are similar in size to the green fluorescent protein (GFP), have single-point attachment to proteins, have a ~54-fold higher photobleaching lifetime and emit ~43-fold more photon...

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Publicat a:Nat Methods
Autors principals: Niekamp, Stefan, Stuurman, Nico, Vale, Ronald D.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138518/
https://ncbi.nlm.nih.gov/pubmed/32203385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-0782-3
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