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The Enzymes Mediating Maturation of the Seryl-tRNA Synthetase Inhibitor SB-217452 during Biosynthesis of Albomycins
Albomycin δ(2) is a sulfur-containing sideromycin natural product that shows potent antibacterial activity against clinically important pathogens. The l-serine-thioheptose dipeptide partial structure, known as SB-217452, has been found to be the active seryl-tRNA synthetase inhibitor component of al...
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| Publicat a: | Angew Chem Int Ed Engl |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7138408/ https://ncbi.nlm.nih.gov/pubmed/31863717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201915275 |
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