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NEK2 induces autophagy‐mediated bortezomib resistance by stabilizing Beclin‐1 in multiple myeloma

NEK2 is associated with drug resistance in multiple cancers. Our previous studies indicated that high NEK2 confers inferior survival in multiple myeloma (MM); thus, a better understanding of the mechanisms by which NEK2 induces drug resistance in MM is required. In this study, we discovered that NEK...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Oncol
Κύριοι συγγραφείς: Xia, Jiliang, He, Yanjuan, Meng, Bin, Chen, Shilian, Zhang, Jingyu, Wu, Xuan, Zhu, Yinghong, Shen, Yi, Feng, Xiangling, Guan, Yongjun, Kuang, Chunmei, Guo, Jiaojiao, Lei, Qian, Wu, Yangbowen, An, Gang, Li, Guancheng, Qiu, Lugui, Zhan, Fenghuang, Zhou, Wen
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138399/
https://ncbi.nlm.nih.gov/pubmed/31955515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12641
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