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Evolutionary repair: Changes in multiple functional modules allow meiotic cohesin to support mitosis

The role of proteins often changes during evolution, but we do not know how cells adapt when a protein is asked to participate in a different biological function. We forced the budding yeast, Saccharomyces cerevisiae, to use the meiosis-specific kleisin, recombination 8 (Rec8), during the mitotic ce...

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Bibliografiske detaljer
Udgivet i:PLoS Biol
Main Authors: Hsieh, Yu-Ying Phoebe, Makrantoni, Vasso, Robertson, Daniel, Marston, Adèle L., Murray, Andrew W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138332/
https://ncbi.nlm.nih.gov/pubmed/32155147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000635
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